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Workshop
[Free Online Workshop] Metabolite Identification: Strategies, Techniques and Case Studies
Speakers:
Cyrus Khojasteh (Genentech), Bill Fitch, Shichang Miao (ChemoCentryx), Shuguang Ma (Genentech) and Greg Walker (Pfizer)
Organizers:
Cyrus Khojasteh (Genentech), Bill Fitch & Shuguang Ma (Genentech)
Date:
2021-03-09- 03/10/2021
Time:
8:30-12:30 Pacific Time
Registration fee:
(USD):
Location:
Online via Zoom
Major Sponsor:
Vendor show vendors registered to date:
Registration: http://www.PBSS.org
Registration deadline:2021-03-07
(it will close sooner if the seating cap is reached)
About the Topic
Identification of the metabolites is a major component in drug metabolism studies and is critical for both drug discovery and drug development. It requires careful strategic planning, utilization of modern analytical techniques in LCMS and NMR, and in-depth data analysis and interpretation. Deep understanding of the fundamentals of drug metabolism and organic chemistry is essential for a successful metabolite ID scientist. This workshop will discuss drug metabolizing enzymes, state-of-the-art techniques for generating, detecting, and identifying metabolites, data mining tools and MS/MS spectral interpretation, stage-based approaches for metabolite identification in drug discovery and development, and strategies for metabolites-in-safety testing.
Agenda(All listed times are Pacific Time (PT))
Day 1, March 09, 2021
8:30am - 8:45am Welcome Remarks and Introduction - Monika Wientzek, PhD (PBSS)
8:45am - 10:00am Introduction to Metabolite Identification - Bill Fitch, PhD (Consultant)
10:00am - 10:10am Major sponsorship presentation - Molecular Discovery
10:10am - 10:30am Break
10:30am - 11:45am MS/MS Interpretation - Shichang Miao, PhD (ChemoCentryx)
11:45am - 12:15pm Panel Discussion - All speakers
Day 2, March 10, 2021
8:30am - 9:45am MIST and novel biotransformation - Shuguang Ma, PhD (Genentech)
9:45am - 9:55am Major sponsorship presentation - Hypha Discovery Ltd
9:55am – 10:20am Break
10:20am – 11:30am Metabolite generation, NMR, and metabolite for lead diversification - Greg Walker, PhD (Pfizer)
11:30am – 12:00pm Panel discussion - All speakers
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