Jobs
View more job listings or post a job
Simcere of America Inc. VP of Boston Innovation Center
Simcere Pharma Group 制剂研发总监或以上 Drug Formulation Director  
Simcere of America Inc. Job Title: Senior Director, Toxicology    
Simcere of America Inc. Associate Director/Director, Regulatory Affairs  
Simcere of America Inc. Director of Business Development
Simcere of America Inc. Job Title: Business Development Intern  
Charles River Laboratories Research Associate
Genomics Institute of the Novartis Research Foundation Senior Investigator (Associate Director) in DMPK
Pliant Therapeutics, Inc. Description: Pliant Therapeutics is an early stage biopharmaceutical company focused on the discovery and development of novel therapies for fibrotic diseases. Founded by Third Rock Ventures with world-renowned academic th
Genentech ASSOCIATE SCIENTIST, DRUG METABOLISM AND PHARMACOKINETICS - BIOANALYSIS (DMPK-BA)
Post a job


Position:
Research Associate II - Senior Research Associate, DMPK

Employer:
Cytokinetics

Description:

This position will support bioanalysis, in vitro ADME studies, formulation, for lead/development compounds in support of Cytokinetics’ discovery and development programs. We are looking for a motivated critical thinker who will conduct established in vitro ADME assays and bioanalytical analysis as well as assist in the development and validation of in vitro and ex vivo assays to characterize pharmaceutical and ADME properties of small molecule therapeutics. The individual will participate as a team member and collaborator multi-disciplinary departments to contribute to a research effort to validate assays in the areas of drug absorption, metabolism, elimination, clearance and drug-drug interactions.

  • Prepare biological samples using different extraction techniques

  • Analyze biological samples and analytical samples by LC-MS/MS and HPLC

  • Design and execute standard ADME assays

  • Participate in scientific discussions at department/ meetings

  • Present experimental data at project meetings

  • Willingness to learn and master advanced automation as applied to ADME

  • Determination to pioneer and develop new and relevant in vitro assays to address Program needs



Qualifications/Experience:
  • BA/BS/MS in relevant field with 2+ years of experience in drug metabolism and pharmacokinetics within a pharmaceutical company preferred or academic equivalent

  • A minimum of 2 years of experience with LC-MS operation (experience with ABSciex/LTQ-Orbitrap a plus)

  • A solid knowledge and hands-on experience with in vitro DMPK assays is preferred

  • Familiarity with a range of laboratory automation instrumentation including robotic liquid handlers - Mechanically inclined

  • Good communication skills and ability to work in a team-based environment is essential

  • Strong analytical capabilities and problem solving skills

  • Highly motivated and energetic

  • Strong work ethic and tenacity



Location: South San Francisco, California

Contact: https://cytokinetics.com/company/careers/job-opportunities/

Post Date: 8/17/2018 8:17:20 AM
©Pharmaceutical & BioScience Society, International; Last Modified: 11/13/2018; Visited: 1280; Admin Logon
Ads (in random order)
Submit a Text Ad
($200 for 2 months)

Simulations Plus From sketching chemical structures, all the way through regulatory filings, Simulations Plus consulting experts can help. Over 20 years of experience!
Origin Bioanalytical Laboratory A contract research organization for bioanalytical LC-MS/MS analysis specializing in ocular tissues/fluids located Rancho Cordova, CA
Sirius Analytical Services and Automated Instruments for pKa, log P/D, solubility, dissolution. New Scissor instrument for sub-cutaneous injection site simulation.
Reaction Biology Corporation (RBC) RBC provides kinase & epigenetic assays and proteins for early-stage programs. Contact: kelvin.lam@reactionbiology.com
Nuventra Pharma Sciences With a background in clinical pharmacology and PK/PD, Nuventra enables our clients to make better strategic decisions.
Pharm-Olam International Pharm-Olam is a midsize CRO offering a wide range of Phase I-IV comprehensive, clinical research services to the pharma, biotech & device industries.
Simulations Plus From the developers of GastroPlus™ comes PKPlus™. NCA & compartmental PK modeling for regulatory submissions. True "PlugNPlay" PK.
Pacific BioLabs Offers toxicology,microbiology,analytical and bioanalytical services with a combination of technical expertise & rigorous quality systems.
UC Davis UC Davis Liquid Chromatography/Mass Spectrometry and Confirmation Supervisor Apply Online: http://50.73.55.13/counter.php?id=139228 UC Davis i
INTERTEK PHARMACEUTICAL SERVICES Intertek, a bioanalytical CRO (drugs, biologics, proteins, ADCs, biosimilar, generics, peptide, biomarker, immunogenicity, ADA, Nab) in San Diego CA
Simulations Plus ADMET Predictor™ 9 - ADMET property estimation, HTPK Simulation, SAR elucidation, and QSAR model building software.
Nektar Therapeutics Sr. Scientist - Bioanalytical Contributes to the development, validation, and implementation of ligand-binding assays. PhD and 5 years exp.
Protein Characterization Seminar hosted by Charles River Join us in San Diego on September 15, 2017 to discuss the analytical methods used to detect process residuals and determine biosimilarity.
Clinverse Inc. A global technology company solely focused on automating the financial management of clinical trials.
Solid Form Solutions Ltd Solid Form Solutions Ltd CRO providing Solid State Crystallization and Analytical Testing Services to the pharma/biotech industries.
Zef Scientific California’s premier multi-vendor LC-MS/MS engineering firm with highest level of services & rapid onsite response on all major brands & models.
Avecia Pharma Services Nitto Avecia Pharma provides GMP contract development and parenteral manufacturing services to the pharma/biotech industries. Visit our Irvine labs!
BIOTECH WEEK BOSTON - Sept. 4-7 Join us at Biotech Week Boston - Where Big Science and Bright Minds Meet. Sept. 4-7, 2018 at Hynes Convention Center.
Pharmaron Our Vision: To become the world-leading small-molecule life science R&D service company, supporting our partners from discovery to commercialization
PHARMA INVENTOR Vancouver based Canadian Custom Synthesis Services Company, Offers Inventive & Cost-Effective Chemical Synthesis Services to Life Sciences Industries.
Hypha Discovery Specialists in provision of drug metabolites at mg-g scale, including CYP/Non-CYP metabolites and conjugates such as glucuronides/sulfates.
S-Matrix Fusion QbD® Software – Analytical Method Development & Validation, Formulation & Process R&D. Works with ChemStation, Chromeleon, and Empower.
Charles River 2nd Annual Viral Summit The 2-day summit unites industry experts in an interactive setting to share updates and discuss trends in viral safety and viral clearance.
Simulations Plus GastroPlus™ PBPK modeling workshops scheduled around the globe to train scientists on the new guidance documents from the FDA and EMA. Register today!
MicroConstants MicroConstants is a GLP-compliant Contract Research Organization focused on performing regulated bioanalysis, drug metabolism and PK analysis.
Submit a Text Ad