Speakers: Valentina Kwak, Freelance Scientific Editor; Hongtao Zhao, AstraZeneca; Justin Reitsma, AbbVie; Jesus Medina, Arvinas; Donglu Zhang, Genentech; Elisia Villemure, Genentech
Organizers: Elizabeth Kelley, PhD, Genentech; Wei Chen, PhD; Steven Richards, PhD.
Date: 2024-09-25- 9/25/2024
Time: 8:30-12:45 Pacific Time
Registration fee: Free
Location: Online via Zoom
Major Sponsor:
Vendor show vendors registered to date:
Registration: http://www.PBSS.org
Registration deadline:2024-09-24  (it will close sooner if the seating cap is reached)

About the Topic

Targeting the destruction of proteins via a degradation mechanism of action has opened up the door to many targets that have proven difficult to drug via traditional inhibition mechanisms. Just as with traditional small molecule inhibitors or modulators, successful development of degraders requires support and collaboration from a variety of disciplines. This symposium will aim to cover not only specific medicinal chemistry development stories of degrader molecules of interest, but also emerging technologies in the fields of computational chemistry and DMPK that aid in the development of this novel class of therapeutic agents. Featuring all industrial speakers actively working in the degradation area, this symposium will be a highly practical look at how both smaller biotechs and larger pharmaceutical companies successfully execute to bring degraders to the clinic.