Job Description Summary: The BS/MS Research Associate- Bioanalytical is responsible for conducting scientific experiments that contribute to research and drug discovery activities at PTC. This position assists in extracting, enriching, and purifying biomarkers for quantitation in translational studies. The incumbent, is also responsible for communicating experimental results to his/her supervisor and the project team.

Primary Duties/responsibilities

The BS/MS Research Associate- Bioanalytical supports adherence to all regulatory requirements and company Standard Operating Procedures (SOPs) including as appropriate.Job Description:

• Under general guidance, executes experiments and communicates results as part of multi-disciplinary team(s).
• Applies relevant scientific principles and techniques to research problems.
• Maintains detailed laboratory notebooks.
• Maintains knowledge of state-of-the-art principles and techniques.
• Presents findings internally and contributes to the publication of the work of the project team in well-established and peer reviewed journals, subject to internal scientific and legal approval.
• Contributes to the development of patent applications as appropriate.
• Complies with all safety requirements.
• Contributes to laboratory needs, such as stock room maintenance and ordering supplies.

Specific duties may also include, but may not be limited to, the following:

• Homogenization and extraction of biomarkers from tissues and biofluids using multiple enrichment and purification techniques.
• Quantitation of multiple analytes from translational studies using both LC-MS/MS and immunoassays.
• Weigh and track biomarker compounds, prepare stocks, and QC assay components.
• Tuning and operation of analytical equipment.

Knowledge/Skills/Abilities Required

• Extensive hands-on experience with multi-analyte extraction methods such as LLE, PPT or SPE from tissue and biofluids.
• Prior experience with analytical detection techniques, especially mass spectrometry (targeted or untargeted).
• Familiarity with liquid chromatography systems.
• Minimum level of education and years of relevant work experience.
• Bachelor’s degree in a scientific discipline with a minimum of 3 years’ relevant experience.
• Special knowledge or skills needed and/or licenses or certificates required.
• Demonstrates technical proficiency, and the ability to collaborate with others on cross functional teams in a fast-paced, matrixed, environment consisting of internal and external team members. Possesses knowledge of scientific principles and concepts and keeps current and utilize relevant scientific literature.
• Proficiency with Microsoft Office.
• Effective verbal and written communication and skills.
• Analytical thinker with problem-solving skills and the ability to adapt to changing priorities and deadlines.
• Effective planning, organization and time management skills including the ability to support and prioritize multiple projects.
• Special knowledge or skills and/or licenses or certificates preferred.
• Candidates with prior experience in metabolic energy, inflammation, or neurological programs are preferred.
• Prior experience with immunoassays especially ELISA.
• Prior experience with liquid automation systems is a plus .
• Travel requirements - Up to 10%

EEO Statement

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.